C7orf24
WebWe have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ … WebAug 6, 2010 · A set of 123 primary breast tumors and matched normal tissue was analyzed by two-dimensional (2D) gel electrophoresis, and a novel protein, C7orf24, was identified as being upregulated in cancer...
C7orf24
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WebAug 8, 2008 · The hypothetical protein C7orf24 has been implicated as a cancer marker with a potential role in cell proliferation. We have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ-glutamyl dipeptides and potentially plays a significant role in glutathione … WebNov 1, 2008 · We have identified C7orf24 as γ-glutamyl cyclotransferase (GGCT) that catalyzes the formation of 5-oxoproline (pyroglutamic acid) from γ-glutamyl dipeptides …
WebSep 1, 2009 · C7orf24 was first identified as a 21-kDa cytochrome c-releasing factor detected in the cytosolic fraction of human leukemia U937 cells after treatment with geranylgeraniol. C7orf24 protein was... WebSep 10, 2024 · Zestimate® Home Value: $260,000. 424 N 7th St, River Falls, WI is a single family home that contains 2,022 sq ft and was built in 1900. It contains 4 bedrooms and 2 …
WebGamma-glutamylcyclotransferase (GGCT; also Cytochrome c-releasing factor 21, CRF21, C7orf24 or LOC79017) is a 21 kDa AIG2-like family member. It is a cytosolic protein that induces the release of Cytochrome c from mitochondria, possibly initiating apoptosis. Human CRF21 is 188 amino acids (aa) in length and is a complex of beta -sheets and ... WebJul 12, 2013 · C7orf24—named after a hypothetical gene product of human chromosome 7 open reading frame 24—was originally identified as a cytoplasmic protein specifically expressed in the urothelial carcinoma ( 1, 2 ). Aberrant expression of C7orf24 has also been reported in a range of cancers, including prostate and breast cancers ( 3–7 ).
WebNov 1, 2011 · Human chromosome 7 ORF 24 (C7orf24) has been identified as a tumor‐related protein, and shown to be a γ‐glutamyl cyclotransferase. In the current study, we characterized the promoter region of the human C7orf24 gene to explore the transcriptional regulation of the gene. We revealed that the human C7orf24 promoter is a …
WebThe identification and structural characterization of C7orf24 as γ-glutamyl cyclotransferase. An essential enzyme in the γ-glutamyl cycle. VOLUME 283 (2008) PAGES 22031-22042. Previous Article Inhibition of Fatty-acid Synthase Induces Caspase-8-mediated Tumor Cell Apoptosis by Up-regulating DDIT4* the rolling stones you got the silverWebJun 1, 2012 · Immunohistochemical analysis revealed that C7orf24 levels were significantly reduced within tumor tissues collected from anti-C7orf24 siRNA-administered mice, indicating that the knockdown of C7orf24 induced cytotoxicity in tumor tissue. In conclusion, these data show for the first time that knockdown of C7orf24 prevents tumor growth in … the rolling stones ytWebJul 26, 2024 · In 2008, C7orf24 was identified as γ-glutamyl cyclotransferase, and this study renamed C7orf24 as GGCT (Oakley et al., 2008. Oakley A.J. Yamada T. Liu D. Coggan M. Clark A.G. Board P.G. The identification and structural characterization of C7orf24 as gamma-glutamyl cyclotransferase. An essential enzyme in the gamma-glutamyl cycle. tracks colisthe rolling tamale monroe laWebC7orf24 is currently registered in the protein database as a hypothetical protein with unknown function. T … Proteome analysis of bladder cancer with narrow-range pH 2-DE … the rollinguuuuWebJan 5, 2024 · C7orf24 encodes γ-glutamylcyclotransferase (GGCT), an enzyme involved in glutathione metabolism that catalyzes the generation of 5-oxoproline and free amino acids from γ-glutamyl peptides . tracks collingwoodWebDec 8, 2008 · GLUTAMYLCYCLOTRANSFERASE, GAMMA; GCTG CHROMOSOME 7 OPEN READING FRAME 24; C7ORF24 CYTOCHROME c-RELEASING FACTOR, 21-KD; CRF21 HGNC Approved Gene Symbol: GGCT Cytogenetic location: 7p14.3 Genomic coordinates (GRCh38): 7:30,496,621-30,504,829 (from NCBI) TEXT Description t racks comprexxor