Cytoplasmic vacuole induction
WebNov 15, 2024 · Cytoplasmic vacuolization usually occurs in cells treated with different agents and substances. We found that LZ-106, an analog of enoxacin, is a potent lysosomotropic agent, contributing to the formation of cytoplasmic vacuoles in cells. Studies of LZ-106-induced vacuolization in H460 cells showed acid environment inside … WebApr 1, 1999 · The small vacuoles, thus newly formed in the cytoplasm, are finally incorporated into the central vacuole. It has been shown that the induction of cellular autophagy is controlled by the supply of mitochondria with respiratory substrate and not by the decrease in the concentration of sucrose and hexose phosphates (Aubert et al., 1996).
Cytoplasmic vacuole induction
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WebMay 27, 2015 · Cytoplasmic vacuolation-mediated cell death and paraptosis have specifically been described to induce cytoplasmic vacuole formation, which is prevented by the protein translation inhibitor CHX 12 ... WebFeb 28, 2024 · Autophagy is an intracellular process that facilitates the bulk degradation of cytoplasmic materials by the vacuole or lysosome in eukaryotes. This conserved process is achieved through the coordination of different autophagy-related genes (ATGs). Autophagy is essential for recycling cytoplasmic material and eliminating damaged or …
WebJan 5, 2024 · We found that YRL1091 induced cytotoxicity in these cells with numerous cytoplasmic vacuoles, one of the distinct characteristics of paraptosis. YRL1091-treated BC cells displayed several other distinguishing features of … WebOf note, both formation of vacuoles and induction of cell death in response to abemaciclib were inhibited by vacuolar-type ATPase (V-ATPase) inhibitors such as bafilomycin A1 and concanamycin A. Live-cell imaging revealed that the abemaciclib-induced vacuoles were derived from lysosomes that expanded following acidification.
WebMay 27, 2015 · Under electron microscopy, curcumin-induced large cytoplasmic vacuoles appeared clear and lacked any detectable cytoplasmic material and without plasma … WebCytoplasmic vacuoles, which are a morphological feature of dysplasia, can be observed under a microscope at initial diagnosis. Recently, this typical morphological feature has …
Webvac·u·ole. n. 1. A membrane-bound organelle in the cytoplasm of most cells, especially plant cells, containing water and dissolved substances such as salts, sugars, enzymes, and amino acids. 2. A small extracellular cavity or space within tissues. [French, from Latin vacuus, empty; see vacuum .] porsche of halifax staffWebCytoplasmic Vacuolation. Vacuoles are areas of the cytoplasm which do not stain with Wright's stain and appear as holes in the cytoplasm. Their composition may vary; some … porsche of houston northWebOct 23, 2014 · comment: Cytoplasmic vacuolation is characterized by the presence of clear vacuoles in renal tubule epithelium in the absence of any morphologic changes … porsche of fresno caWebJul 1, 2024 · Vacuoles are seen in myeloid and erythroid progenitor cells from bone marrow aspirates. E1 enzyme refers to the ubiquitin activating enzyme encoded by UBA1 , which … irish brothers llc construction port orchardWebMay 27, 2015 · Cytoplasmic vacuolation-mediated cell death and paraptosis have specifically been described to induce cytoplasmic vacuole formation, which is … irish brothers constructionWebThe cytoplasm-to-vacuole targeting pathway and its overlap with macroautophagy The cytoplasm-to-vacuole targeting (Cvt) pathway was discovered as the biosynthetic … irish brothers port orchardWebMay 27, 2015 · Curcumin-induced cytoplasmic vacuolation requires new protein synthesis and is prevented by LC3 knockdown Cytoplasmic vacuolation-mediated cell death and paraptosis have specifically been described to induce cytoplasmic vacuole formation, which is prevented by the protein translation inhibitor CHX 12, 13, 17. irish brothers paving