Florence imrt trial

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August undefined, 2024

WebAug 24, 2024 · PURPOSE To report the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) Florence … WebAug 24, 2024 · The Florence trial showed equivalent outcomes for WBI (50 Gy in 25 fractions with tumor bed boost) vs. APBI (30 Gy in five every-other-day fractions) using IMRT.

Patient-Reported Toxicity During Pelvic Intensity …

WebA Phase II Randomized Trial of Proton vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas. Goal: To compare if proton beam radiation therapy is more effective than photon-based beam intensity-modulated radiation therapy in treating patients with glioma. incompatibility\\u0027s 7l

Comparing Proton Therapy to Photon Radiation Therapy for …

WebOct 1, 2024 · Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial. Radiother Oncol, 121 (2016), pp. 414-419. Article. ... Long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol, 38 (2024), pp. 4175-4183. WebOct 17, 2024 · To date, only the Florence IMRT-APBI phase 3 trial reported the outcomes of exclusive IMRT accelerated PBI compared to WBI, demonstrating no significant difference between the two groups in terms of ipsilateral breast tumor recurrences (IBTR). The PBI group presented significantly better results considering acute (p=0.0001), late (p=0.004), … WebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission tomography scans, also called PET scans, to create a treatment plan that targets just the cancer. Proton beam therapy facilities at Mayo Clinic use intensity-modulated pencil beam scanning. incompatibility\\u0027s 6y

Five-Fraction Prone Accelerated Partial Breast Irradiation: …

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WebJun 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast irradiation schedule, with long-term … WebJun 1, 2010 · Purpose: To evaluate with a randomized clinical trial the possibility of treating the index quadrant with external intensity-modulated radiotherapy (IMRT) in a selected group of patients with early-stage breast cancer and to analyze the acute toxicity. Methods and materials: From September 2005, a randomized Phase III clinical trial has been … incompatibility\\u0027s 7aWebDec 11, 2024 · A fourth study, the Florence trial, 13 used the QLQ-BR23 subscale, but only at baseline and 2 years after completion of treatment. Patients were randomly assigned to partial-breast IMRT using 30 Gy in … incompatibility\\u0027s 79

"WebJan 14, 2024 · This trial studies how well proton beam radiation therapy compared with intensity modulated photon radiotherapy works in treating patients with stage I-IVA esophageal cancer. Proton beam radiation therapy uses a beam of protons (rather than x-rays) to send radiation inside the body to the tumor without damaging much of the … " - Florence imrt trial

Florence imrt trial

Updates on the APBI-IMRT-Florence Trial (NCT02104895 …

WebNational Center for Biotechnology Information WebMar 9, 2024 · Mayo Clinic doctors use the latest imaging techniques to carefully plan radiation treatments. Doctors use CT scans, MRI scans and positron emission …

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WebAug 2, 2024 · Partial-breast radiotherapy after breast conservation surgery for patients with early breast cancer (UK IMPORT LOW trial): 5-year results from a multicentre, randomised, controlled, phase 3, non-inferiority trial. Lancet. 2024 Sep 9;390(10099):1048-1060. doi: 10.1016/S0140-6736(17)31145-5. Epub 2024 Aug 2. WebMay 13, 2024 · Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial. Radiother Oncol 2016; 121:414–419. [Google Scholar] 19. Patel ... Long-term results of the randomized phase III APBI-IMRT-Florence trial. J Clin Oncol 2024; 38:4175–4183.

WebDec 15, 2024 · APBI-IMRT Florence Trial Primary endpoint: Ipsilateral breast tumor recurrence Median follow up: 10.7 years Meattiniet al., JCO 2024 520 patients enrolled 30 Gy in 5 fxQOD PBI, 1.5 weeks (n=260) 50Gy in 25 fx WBI, 5 weeks (n=260) 47 Toxicity Reduction in Breast Cancer APBI-IMRT Florence Trial Efficacy Meattiniet al., JCO 2024 48 WebFeb 11, 2024 · ORCID: 0000–0001-6019–7309. In the treatment of breast cancer, intensity-modulated radiation therapy (IMRT) reportedly reduces the high-dose irradiation of at-risk organs and decreases the ...

WebSep 15, 2024 · In the Florence trial, 30 Gy in five daily fractions was used for PBI with intensity-modulated radiotherapy (IMRT), and treatment-related toxicity and cosmesis outcomes were found to be significantly in favor of … WebMar 28, 2024 · It is worth noting that ultra-fractionated EBRT options have also been increasingly adopted following the publication of the APBI-Florence-IMRT trial that demonstrated equivalent local control and survival of a 5-fraction partial-breast EBRT regimen compared to conventional whole-breast irradiation (21). In this trial, the five …

WebFeb 15, 2024 · Abstract. Background. Partial breast irradiation (PBI) is a reasonable alternative for a whole breast irradiation (WBI) in selected early stage breast cancer patients. The 5-year analysis of the APBI IMRT Florence phase 3 trial showed no significant difference in terms of ipsilateral tumor recurrence (IBTR) and survival rates between the …

WebAPBI-IMRT-Florence trial Delivery technique In the original protocol (NCT02104895), ﬁve 6-MV step-and-shoot IMRT coplanar ﬁelds were used.10 A dose of 30 Gy in 5 nonconsecutive, once-daily fractions was prescribed. At the time of the study design, the every-other-day approach was chosen to be cautious in regard to the toxicity proﬁle. incompatibility\\u0027s 7rWebJan 1, 2024 · The APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective … incompatibility\\u0027s 7bWebThe APBI-IMRT-Florence trial (NCT02104895) schedule (30 Gy in 5 fractions) might represent an appealing treatment option, being both a safe and effective partial breast … incompatibility\\u0027s 7kWebOct 22, 2024 · Meattini I, Poortmans PMP, Marrazzo L, Desideri I, Brain E, Hamaker M, Lambertini M, Miccinesi G, Russell N, Saieva C, Strnad V, Visani L, Kaidar-Person O, … incompatibility\\u0027s 7jWebDec 5, 2024 · A trial of interstitial brachytherapy and another of non-accelerated (over 3 weeks) external beam partial breast radiotherapy reported similar rates of local recurrence compared with whole breast irradiation, but median follow-up was 6–6·6 years and few events were observed. ... (IMRT). External beam radiotherapy is non-invasive and uses ... incompatibility\\u0027s 7hWebJan 28, 2024 · The Florence IMRT trial which delivered EB-APBI with 5 fractions of 6 Gy every other day showed similar results to conventionally fractionated whole-breast … incompatibility\\u0027s 7eWebAug 30, 2024 · who randomized patients to intensity modulated radiation therapy (IMRT) APBI (30 Gy in 5 nonconsecutive daily fractions) versus conventionally fractionated WBI. … incompatibility\\u0027s 7v