WebAbout. Years employed in the Life Sciences, with the majority in the field of Bioinformatics and Genomics. Experience in the assembly, finishing and annotation world of large scale genome projects from the humble beginnings of WGS in reference genomes (clone by clone) to NGS to third generation projects involving long reads and related ... Web7 de fev. de 2024 · Long-read technologies are overcoming early limitations in accuracy and throughput, broadening their application domains in genomics. Dedicated analysis tools that take into account the characteristics of long-read data are thus required, but the fast pace of development of such tools can be overwhelming. To assist in the design and …
Accurate long-read de novo assembly evaluation with Inspector
Web28 de nov. de 2024 · NextPolish is a tool that efficiently corrects sequence errors in genomes assembled with long reads by consisting of two interlinked modules designed to score and count K-mers from high quality short reads, and to polish genome assemblies containing large numbers of base errors. MOTIVATION While long-read sequencing … Web7 de fev. de 2024 · long-read-tools.org is an open-source project under the MIT License, whose code is available through GitHub . We encourage researchers to contribute new … body example
NextPolish: a fast and efficient genome polishing tool for long-read …
Web12 de mar. de 2024 · Long-read assembly can underpin the construction of accurate and complete sequences of multiple genomes of a species to build pan-genome infrastructures in Triticeae crops and their wild relatives. ... we are proposing that long-read sequence assemblies should become a tool for “traditional” barley genetics, ... Web20 de set. de 2024 · Gap-Free Long-read Assembler (GALA) GALA is a Ga p-free L ong-read A ssembler. GALA builds a multi-layer graph from different preliminary assemblies, long-reads, and potentially other sources of information, such as Hi-C assemblies. During this process, it identifies mis-assembled contigs and trim them. The corrected data are … Web14 de nov. de 2024 · Long-read de novo genome assembly continues to advance rapidly. However, there is a lack of effective tools to accurately evaluate the assembly results, especially for structural errors. We present Inspector, a reference-free long-read de novo assembly evaluator which faithfully reports types of errors and their precise locations. glazed ham steaks pan fried