WebSep 24, 2014 · In a move partially implemented to help editors and manuscript reviewers … WebJan 11, 2024 · Curcumin is a constituent (up to ∼5%) of the traditional medicine known as …
New substructure filters for removal of pan assay interference
WebThus it is with great caution and diligence that compounds possessing a known PAINS … Pan-assay interference compounds (PAINS) are chemical compounds that often give false positive results in high-throughput screens. PAINS tend to react nonspecifically with numerous biological targets rather than specifically affecting one desired target. A number of disruptive functional groups are shared by many … See more • Drug discovery See more • Yang JJ, Ursu O, Lipinski CA, Sklar LA, Oprea TI, Bologa CG (2016). "Badapple: promiscuity patterns from noisy evidence". Journal of … See more lite-brite wall art
PAINs And Good Old Med Chem Science AAAS
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