WebJan 8, 2024 · To examine the role of YTHDF2 in GBM tumorigenesis, we used two distinct short hairpin RNAs targeting the 3′UTR (shYTHDF2#1) or the CDS (shYTHDF2#2) of … WebFigure 2 . YTHDF2 inhibited the activity of endometrial cell. (A,B) qRT-PCR and immunoblot analysis of YTHDF2 in endometrial cell HEC-1-A transfected with lentiviral shControl, YTHDF2 shRNA #1 or #2 as indicated for 72 h.(C,H) Cell proliferation measured by CCK8 assay of HEC-1-A cells stably expressing shYTHDF2 (C) or YTHDF2 (H) as indicated.The …
YTHDF2 siRNA and shRNA Plasmids (m) - SCBT
WebApr 3, 2024 · A RPMI-8226 cells transfected with shNC or shYTHDF2 were injected in the left or right flanks of BALB/c nude mice (n = 4). B Mice were sacrificed when tumor diameter … WebYTHDF2, also named as YTH domain-containing family protein 2, is a 579 amino acid protein, which contains 1 YTH domain. YTHDF2 specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a … bischof caroline begnins
余健秀研究组发现m6A修饰阅读蛋白YTHDF2功能调控的新分子机 …
WebNov 18, 2024 · YTHDF2 inhibits IL-11 and Serpin E2 expression in HCC cells. (a) Volcano plots showing up (red) - or down (blue) -regulated genes in SMMC7721-shYTHDF2 versus … WebMar 23, 2024 · Nature 子刊 客户文章:m6A 修饰参与调控急性缺血卒中恢复的作用机制,采用MeRIP-Seq高通量测序发现,在急性缺血卒中(Acute Ischemic Stroke, AIS)患者的梗死周围皮质组织和动物模型中,mRNA的m6A修饰水平相比对照组显著提高,作者在其中筛选得到了Plpp3(编码促进卒中动物模型血管修复的LPP3蛋白) WebNov 18, 2024 · YTHDF2 inhibits IL-11 and Serpin E2 expression in HCC cells. (a) Volcano plots showing up (red) - or down (blue) -regulated genes in SMMC7721-shYTHDF2 versus SMMC7721-shCtrl cells, as assessed by RNA-seq. (b) GO analysis based on the RNA-seq in (A), showing the most significant GO terms and the P values. dark brown colored pencil