Thiamin pyrophosphokinase 1

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August undefined, 2024

Web20 Jun 2024 · Vitamin B 1 (Thiamine) is the first B Vitamin to be discovered by researchers. “Thio-vitamine” refers to its sulfur-containing content.It’s called B 1 because it was the first of the B complex vitamins to be … WebCatalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate. The protein encoded by …

Presence of thiamine pyrophosphate in mammalian peroxisomes

Web8 Feb 2024 · Crystal Structure of Thiamine pyrophosphokinase from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR677 Kuzin A, Abashidze M, … Web16 Apr 2001 · 1IG3. PubMed Abstract: Thiamin pyrophosphate (TPP) is a coenzyme derived from vitamin B1 (thiamin). TPP synthesis in eukaryotes requires thiamin … ars bulgaria ltd

Thiamine pyrophosphokinase deficiency induces …

WebTPK1 thiamin pyrophosphokinase 1 [ Homo sapiens (human) ] Gene ID: 27010, updated on 29-Mar-2024 Download Datasets Summary Official Symbol TPK1 provided by HGNC … Web1. Haematopoietic And Lymphoid (7.3e-32) n=115 2. Solid (7.3e-32) n=963 3. Lymphoid (1.1e-28) n=78 4. B-Lymphoblastic Leukemia/Lymphoma (4.9e-18) n=12 5. Non-Hodgkin … Web11 Apr 2024 · Thiamine 1 (vitamin B 1) is essential for energy metabolism, and its deficiency leads to neurological disorders. (1−3) Thiamine, being positively charged, requires transport into the cytoplasm, where it is converted into coenzyme thiamine diphosphate (ThDP) 2a by thiamine pyrophosphokinase (TPK) ( Figure 1 A). (1−5) ThDP-dependent enzymes include … ars besançon

Anti-TPK1 antibody produced in rabbit - Sigma-Aldrich

Thiamin pyrophosphokinase 1

Web9 Dec 2011 · Thiamine pyrophosphate (TPP) is an essential cofactor of the cytosolic transketolase and of three mitochondrial enzymes involved in the oxidative decarboxylation of either pyruvate,... WebThiamin diphosphate (TPD), also called thiamin pyrophosphate (TPP), is the coenzymatic form of vitamin B1 and constitutes about 80% of total body thiamine. It is a key factor in …

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WebThiamin pyrophosphokinase 1. Definition: Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to … WebThiamine diphosphokinase activity Specific Function Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of …

WebNM_022445.4(TPK1):c.351A>G (p.Leu117=) AND Childhood encephalopathy due to thiamine pyrophosphokinase deficiency. Clinical significance: Likely benign (Last evaluated: Feb 10, 2024) WebDescription. Predicted to have thiamine diphosphokinase activity. Predicted to be involved in thiamine diphosphate biosynthetic process. Human ortholog (s) of this gene implicated in …

WebThiamine pyrophosphokinase 1 Gene TPK1 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 267 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Download Add a publication Entry feedback Function Web20 May 2011 · Revision History (Full details and data files). Version 1.0: 2011-06-08 Type: Initial release; Version 1.1: 2011-07-13 Changes: Version format compliance ; Version 1.2: …

Web11 May 2024 · Thiamine pyrophosphokinase-1 (TPK1), a key component of Vitamin B1/thiamine metabolism, was identified as a target for radiosensitization. TPK1 knockdown caused significant radiosensitization in cancer but not normal tissue cell lines. Other means of blocking this pathway, knockdown of thiamine transporter-1 (THTR1) or treatment with …

WebThiamine, also known as vitamin B1, plays a key role in the human metabolism. It is present in many dietary sources such as meats, eggs, fish, beans and peas, nuts, and whole grains. Upon administration thiamine is converted by thiamine pyrophosphokinase-1 (TPK1) to the active form, thiamine pyrophosphate, which serves as a cofactor for enzymes ... bam nameWeb11 May 2024 · Thiamine pyrophosphokinase-1 (TPK1), a key component of Vitamin B1/thiamine metabolism, was identified as a target for radiosensitization. TPK1 … bam name meaningWebThiamin pyrophosphokinase 1. Details Name Thiamin pyrophosphokinase 1 Kind protein Organism Humans Protein. Name UniProt ID; Thiamin pyrophosphokinase 1: Q9H3S4: … ars cantate kalpa